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1

The promises and pitfalls of RNA-interference-based therapeutics

Castanotto, Daniela, Rossi, John J.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.58 MB

english, 2009

2

Structural Similarities Between Hammerhead Ribozymes and the Spliceosomal RNAs Could Be Responsible for Lack of Ribozyme Cleavage in Yeast

CASTANOTTO, DANIELA, LI, HAITANG, CHOW, WARREN, ROSSI, JOHN J., DESHLER, JAMES O.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 7.58 MB

english, 1998

3

Unusual Interactions Between Cleavage Products of a Cis-Cleaving Hammerhead Ribozyme

CASTANOTTO, DANIELA, CHOW, WARREN A., LI, HAITANG, ROSSI, JOHN J.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 9.73 MB

english, 1998

4

SPIE Proceedings [SPIE Photonics East '95 - Philadelphia, PA (Sunday 22 October 1995)] Modeling, Simulation, and Control Technologies for Manufacturing - DFX via the Internet

Wagner, Rick, Castanotto, Giuseppe, Goldberg, Kenneth A., Lumia, Ronald

Year:

1995

Language:

english

File:

PDF, 66 KB

english, 1995

5

Alteration of branch site consensus sequence and enhanced pre-mRNA splicing of an NMDAR1 intron not associated with schizophrenia

Linda Hammond, Daniela Castanotto, Sharmon R. Rice, Vishwajit L. Nimgaonkar, Donna A. Wirshing, John J. Rossi, Leonard L. Heston, Janet L. Sobell

Journal:

American Journal of Medical Genetics Part A

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

6

FixtureNet: interactive computer-aided design via the World Wide Web

RICK WAGNER, GIUSEPPE CASTANOTTO, KEN GOLDBERG

Journal:

International Journal of Human-Computer Studies

Year:

1997

Language:

english

File:

PDF, 6.70 MB

english, 1997

7

RNA-Mediated Inhibition of HIV in a Gene Therapy Setting

ALESSANDRO MICHIENZI, DANIELA CASTANOTTO, NANCY LEE, SHIRLEY LI, JOHN A. ZAIA, JOHN J. ROSSI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 5.03 MB

2003

8

Illicit Drug Use: Can it Predict Adherence to Antiretroviral Therapy?

Michela Martini, Elena Recchia, Paola Nasta, Daniela Castanotto, Francesca Chiaffarino, Fabio Parazzini, Vittorio Agnoletto

Journal:

European Journal of Epidemiology

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

9

Novel ribozyme, RNA decoy, and siRNA approaches to inhibition of HIV in a gene therapy setting

Alessandro Michienzi, Daniela Castanotto, Nancy Lee, Shirley Li, John A. Zaia, John J. Rossi

Journal:

Clinical and Applied Immunology Reviews

Year:

2003

Language:

english

File:

PDF, 507 KB

english, 2003

10

Ribozymes expressed within the loop of a natural antisense RNA form functional transcription terminators

James O. Deshler, Haitang Li, John J. Rossi, Daniela Castanotto

Journal:

Year:

1995

Language:

english

File:

PDF, 1.26 MB

english, 1995

11

Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue

Garry P. Larson, Daniela Castanotto, John J. Rossi, Mokenge P. Malafa

Journal:

Year:

1994

Language:

english

File:

PDF, 960 KB

english, 1994

12

Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor–kappa B (NF-кB)

Roopashree S. Dwarakanath, Saurabh Sahar, Marpadga A. Reddy, Daniela Castanotto, John J. Rossi, Rama Natarajan

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2004

Language:

english

File:

PDF, 597 KB

english, 2004

13

810. Comparison of Anti-HIV Activity from Various Lentiviral Vectors Carrying Anti-HIV shRNA In Vitro

Li, Shirley, Li, Haitang, Castanotto, Daniela, Meinking, Keith, Sun, Guihua, Zaia, John A., Rossi, John J.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

14

Amplification of RNAi—Targeting HLA mRNAs

GONZALEZ, S, CASTANOTTO, D, LI, H, OLIVARES, S, JENSEN, M, FORMAN, S, ROSSI, J, COOPER, L

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 484 KB

english, 2005

15

Short hairpin RNA-directed cytosine (CpG) methylation of the gene promoter in HeLa cells

CASTANOTTO, D, TOMMASI, S, LI, M, LI, H, YANOW, S, PFEIFER, G, ROSSI, J

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

16

CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs

Castanotto, D., Lingeman, R., Riggs, A. D., Rossi, J. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 484 KB

english, 2009

17

Functional siRNA expression from transfected PCR products

CASTANOTTO, DANIELA, LI, HAITANG, ROSSI, JOHN J.

Journal:

Year:

2002

Language:

english

File:

PDF, 1.45 MB

english, 2002

18

Antisense oligonucleotides in cancer

Castanotto, Daniela, Stein, Cy A.

Journal:

Current Opinion in Oncology

Year:

2014

Language:

english

File:

PDF, 203 KB

english, 2014

19

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

Stein, C. A., Hansen, J. B., Lai, J., Wu, S., Voskresenskiy, A., Hog, A., Worm, J., Hedtjarn, M., Souleimanian, N., Miller, P., Soifer, H. S., Castanotto, D., Benimetskaya, L., Orum, H., Koch, T.

Journal:

Nucleic Acids Research

Year:

2010

Language:

english

File:

PDF, 3.79 MB

english, 2010

20

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC

Castanotto, D., Sakurai, K., Lingeman, R., Li, H., Shively, L., Aagaard, L., Soifer, H., Gatignol, A., Riggs, A., Rossi, J. J.

Journal:

Nucleic Acids Research

Year:

2007

Language:

english

File:

PDF, 4.83 MB

english, 2007

21

Small sequence insertions within the branch point region dictate alternative sites of lariat formation in a yeast intron

Castanotto, Daniela, Rossi, John J.

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 6.89 MB

english, 1992

22

Cooperative interaction of branch signals in the actin intron of Saccharomyces cerevisiae

Journal:

Nucleic Acids Research

Year:

1998

Language:

english

File:

PDF, 172 KB

english, 1998

23

A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells

D. Castanotto, M. Lin, C. Kowolik, L. Wang, X. Ren, H. S. Soifer, T. Koch, B. R. Hansen, H. Oerum, B. Armstrong, Z. Wang, P. Bauer, J. Rossi, C. Stein

Year:

2015

Language:

english

File:

PDF, 10.99 MB

english, 2015

24

Sensor and Sensitivity: A Screen for Elite shRNAs

Castanotto, Daniela

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

25

[Methods in Enzymology] RNA Interference Volume 392 || Targeting Cellular Genes with PCR Cassettes Expressing Short Interfering RNAs

Castanotto, Daniela

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

26

Enhancing siRNA effects in T cells for adoptive immunotherapy

Morris, Kevin, Castanotto, Daniela, Al-Kadhimi, Zaid, Jensen, Michael, Rossi, John, Cooper, Laurence J.N.

Journal:

Hematology (American Society of Hematology)

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

27

Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-Mediated Silencing in Mammalian Cells

Castanotto, Daniela, Lin, Min, Kowolik, Claudia, Koch, Troels, Hansen, Bo Rode, Oerum, Henrik, Stein, C A

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

28

[Methods in Enzymology] Antisense Technology Part A: General Methods, Methods of Delivery, and RNA Studies Volume 313 || Intracellular expression and function of antisense catalytic RNAs

Castanotto, Daniela

Year:

2000

Language:

english

File:

PDF, 1.28 MB

english, 2000

29

Illicit Drug Use: Can It Predict Adherence to Antiretroviral Therapy?

Michela Martini, Elena Recchia, Paola Nasta, Daniela Castanotto, Francesca Chiaffarino, Fabio Parazzini and Vittorio Agnoletto

Journal:

European Journal of Epidemiology

Year:

2004

Language:

english

File:

PDF, 562 KB

english, 2004

30

Intracellular ribozyme applications

Castanotto, D., Li, J. R., Michienzi, A., Langlois, M.-A., Lee, N. S., Puymirat, J., Rossi, J. J.

Journal:

Biochemical Society Transactions

Year:

2002

Language:

english

File:

PDF, 1.02 MB

english, 2002

31

692. A Novel RNAi Trigger Design Retains Potent, Target Specific Activity Despite Emerging Mutations in the Target Site

Jung, Ulrike, Castanotto, Daniela, Jung, Marc, Burnett, John, Rossi, John J.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 273 KB

english, 2015

32

6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells

Zhang, Xiaowei, Castanotto, Daniela, Nam, Sangkil, Horne, David, Stein, Cy

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

33

Defibrotide (Defitelio): A New Addition to the Stockpile of Food and Drug Administration-approved Oligonucleotide Drugs

Stein, Cy, Castanotto, Daniela, Krishnan, Amrita, Nikolaenko, Liana

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 128 KB

english, 2016

34

FDA-Approved Oligonucleotide Therapies in 2017

Stein, Cy A., Castanotto, Daniela

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 357 KB

english, 2017

35

[Advances in Pharmacology] Volume 25 || Antisense Catalytic RNAs as Therapeutic Agents

Castanotto, Daniela

Year:

1994

Language:

english

File:

PDF, 1.83 MB

english, 1994

36

Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy

Pang, Ka Ming, Castanotto, Daniela, Li, Haitang, Scherer, Lisa, Rossi, John J.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 2.41 MB

english, 2017

37

Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis

Zhang, Xiaowei, Castanotto, Daniela, Liu, Xueli, Shemi, Amotz, Stein, Cy A

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 5.76 MB

english, 2018

38

A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus

Castanotto, Daniela, Zhang, Xiaowei, Alluin, Jessica, Zhang, Xizhe, Rüger, Jacqueline, Armstrong, Brian, Rossi, John, Riggs, Arthur, Stein, C. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

39

Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019

Rüger, Jacqueline, Ioannou, Silvia, Castanotto, Daniela, Stein, Cy A.

Journal:

Trends in Pharmacological Sciences

Year:

2019

File:

PDF, 2.05 MB

2019

40

A Multifunctional LNA Oligo-Based Strategy Blocks Androgen Receptor Expression And Transactivation Activity In Prostate Cancer Cells

Castanotto, Daniela, Zhang, Xiaowei, RÃ¼ger, Jacqueline, Alluin, Jessica, Sharma, Ritin, Pirrotte, Patrick, Joenson, Lars, Ioannou, Silvia, Nelson, Michael S., VikesÃ¥, Jonas, Hansen, Bo Rode, Koch, T

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 29.62 MB

2020